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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR4
All Species:
24.24
Human Site:
S439
Identified Species:
48.48
UniProt:
P22455
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22455
NP_002002.3
802
87954
S439
L
V
R
G
V
R
L
S
S
S
G
P
A
L
L
Chimpanzee
Pan troglodytes
XP_518127
807
88293
E499
L
A
R
Q
F
S
L
E
S
G
S
S
G
K
S
Rhesus Macaque
Macaca mulatta
XP_001087243
802
87975
S439
L
V
R
G
V
R
L
S
S
S
G
P
A
L
L
Dog
Lupus familis
XP_546211
858
94257
S496
L
V
R
G
V
R
L
S
S
S
G
P
P
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q03142
799
88643
S436
L
V
R
G
V
R
L
S
S
S
G
P
P
L
L
Rat
Rattus norvegicus
Q498D6
800
88690
S437
L
V
R
G
V
R
L
S
S
S
G
P
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
L437
P
L
V
R
I
T
R
L
S
S
S
D
G
P
M
Frog
Xenopus laevis
Q91743
828
93399
S462
L
I
R
I
T
R
L
S
S
S
C
A
P
M
L
Zebra Danio
Brachydanio rerio
Q90413
922
103447
S550
L
M
R
V
A
R
L
S
S
S
C
S
P
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
E424
V
L
G
A
T
L
G
E
G
A
F
G
R
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
S591
E
N
S
D
D
E
P
S
P
Y
Q
I
Q
I
I
Sea Urchin
Strong. purpuratus
Q26614
972
110463
L607
S
T
Q
S
I
A
P
L
F
G
G
R
N
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
97.3
86.7
N.A.
89.7
88.7
N.A.
N.A.
61.5
63.8
56.4
N.A.
35.5
N.A.
30.9
34.2
Protein Similarity:
100
89.7
98.3
88.5
N.A.
92.5
91.6
N.A.
N.A.
72.9
74.6
68.6
N.A.
52.1
N.A.
46.1
49.2
P-Site Identity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
53.3
53.3
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
33.3
66.6
66.6
N.A.
33.3
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
9
9
0
0
0
9
0
9
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
9
0
0
0
0
9
0
17
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
0
0
9
42
0
0
9
0
9
17
50
9
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
17
0
0
0
0
0
0
9
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% K
% Leu:
67
17
0
0
0
9
67
17
0
0
0
0
0
42
67
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
17
9
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
9
0
0
0
0
0
17
0
9
0
0
42
42
9
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
67
9
0
59
9
0
0
0
0
9
9
9
0
% R
% Ser:
9
0
9
9
0
9
0
67
75
67
17
17
0
0
9
% S
% Thr:
0
9
0
0
17
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
42
9
9
42
0
0
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _